Name: Jisely Brito Zamboni
Type: MSc dissertation
Publication date: 19/09/2018
Advisor:
Name |
Role |
|---|---|
| Liliana Aparecida Pimenta de Barros | Advisor * |
Examining board:
| Name |
Role |
|---|---|
| Elizabeth Pimentel Rosetti | Internal Examiner * |
| Liliana Aparecida Pimenta de Barros | Advisor * |
| Valéria Valim Cristo | External Examiner * |
Summary: Primary Sjögren's Syndrome (SSp) is a chronic, autoimmune inflammatory disease that causes reduced secretion of the salivary and lacrimal glands. Despite the important role of saliva on oral health, it is still not confirmed whether SSp exerts influence on the periodontal condition of individuals with SSp. The aim of the present study was to evaluate clinically the oral health status of SSp patients compared to a control group. The sample consisted of 29 female patients with SSp (G1) and 30 control patients (G2), matched by age, gender and socioeconomic status. The groups were compared for oral manifestations, unstimulated whole saliva, index of decayed and missing teeth (DMFT), plaque index (PI), gingival index (GI), bleeding probing (BOP), depth of probing (PS), clinical insertion level (CIL) and case definition
of periodontitis. Chi square test or Fisher exact test was used for the categorical variables, and for the continuous variables, Student t test for comparison of means. The confidence interval established for all calculations was 95% (p≤0.05). The G1 presented more cases of xerostomia (p = 0.0001), oral candidiasis (p = 0.042) and fissured tongue (p = 0.026). In addition, G1 had a lower average of unstimulated whole saliva (p = 0.001) tooth decay (p = 0.019). The G2 had more cases of flavonoid (p = 0.009), higher mean PI (p = 0.047) and SS (p = 0.026). Although not statistically significant, G1 presented more cases of moderate / severe periodontitis and stage IV periodontitis. In addition, it was the only one to present cases of tooth mobility (13.8%) and suppuration (3.4%). The results obtained did not reach statistical significance to confirm the relationship between SSp and periodontitis. G1 presented lower unstimulated whole saliva, greater caries involvement and oral candidiasis, compared to G2. The groups evaluated were statistically similar in
relation to periodontal indices, but a larger number of patients with periodontitis severity were observed in the G1 group. Key words: Sjogrens Syndrome; Periodontitis; Periodontal Diseases; Xerostomia; Saliva; Oral manifestations
