Name: Niverso Rodrigues Simão
Type: MSc dissertation
Publication date: 15/12/2016
Advisor:
Name |
Role |
|---|---|
| Daniela Nascimento Silva | Advisor * |
Examining board:
| Name |
Role |
|---|---|
| Daniela Nascimento Silva | Advisor * |
| Danielle Resende Camisasca Barroso | Internal Examiner * |
| Rossiene Motta Bertollo | External Examiner * |
Summary: Introduction: A conservative approach for the treatment of large jaws cysts is the surgical decompression that can promote the reduction in intracystic pressure, and consequent reduction of the lesion and possible histopathological changes of the epithelial lining and fibrous capsule. Objective: Assessing the histological changes of the cyst lining of odontogenic cystlike lesions before and after decompression. Methods: The authors was performed a retrospective cohort study using histological data records and slides of cystic lesions underwent surgical decompression of patients treated in the discipline of Oral and Maxillofacial Surgery II and Oral Diagnosis Center of UFES between July / 2010 and July / 2016. Clinical and demographic data of patients were obtained and the histopathological changes of the epithelial lining of cysts underwent surgical decompression analyzed with the aid of Binocular Microscope Primo Star (Carl Zeiss). The data were compared using the McNemar test (p-value <0.05). Results: The sample included 10 patients and 11 cystic lesions, which are more prevalent in males (54.55%), with a mean age of 31.1
years and time of decompression on average 12.7 months. There was agreement on the final diagnosis with the initial diagnosis in 9 lesions (81.81%). After decompression some changes cystic capsule were significant as compared to the before decompression aspect: intense inflammation development (p = 0.0468), the distribution of inflammation focal (p = 0.04364), location of the inflammatory infiltrate subepithelial (p = 0.02334), justaepitelial (p = 0.04123) and perivascular (p = 0.04364). Conclusion: There was agreement between the initial and the final diagnosis in most lesions. Surgical decompression increase the intensity inflammation in the capsule and shows a tendency to increase the thickness of the epithelial lining of the cystic lesions
